COMING TREND

1) Video as application ( This means interface design, too )

2) Searchable video

3) AJAX working even harder to act like an object-oriented language for rich experiences

4) Mobile compliance on all fronts ( which includes animation with CSS, think Web 0.5 on your phone )

5) Seamless web-to-desktop applications

6) Mitigating the conversation of a brand into the sale of a product through social application and tracking the purchase from online to offline and back again.

7) Adsense moving to display ads. This is very possible and would change a lot, really quickly, again. UPDATED 9.18.09 New York Times Article